Sarah Beattie

Assistant Professor, University of Iowa

The Beattie Lab is interested in understanding the pathogenesis Aspergillus fumigatus and identifying novel antifungals for the treatment of these infections. We use high throughput screening against A. fumigatus to identify novel molecules with anti-mold activity then apply biochemical, genetic, and microbiological techniques to understand how these compounds work against fungi. Our lab is also interested in understanding how A. fumigatus crosses the blood-brain barrier and establishes infection in the brain. Using murine models combined with in vitro cell culture models, our goal is to identify fungal determinants that are critical cerebral pathogenesis of A. fumigatus.